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Statins and Neuropathy

 

Statins and peripheral neuropathy.

Jeppesen U, Gaist D, Smith T, Sindrup SH.

, Gaist D, Smith T, Sindrup SH.

Department of Neurology, Odense University Hospital, Denmark.

Within the past 3 years seven cases of reversible peripheral neuropathy apparently caused by statins have been reported. Here we report seven additional cases associated with long-term statin therapy, in which other causes of neuropathy were thoroughly excluded. The neuropathy was in all cases axonal and with affection of both thick and thin nerve fibers. The symptoms of neuropathy persisted during an observation period lasting from 10 weeks to 1 year in four cases after statin treatment had been withdrawn. We suggest that long-term statin treatment may be associated with chronic peripheral neuropathy.

PMID: 10027656 [PubMed - indexed for MEDLINE]

http://www.sciencedaily.com/releases/2002/05/020514075710.htm

http://healthlibrary.epnet.com/print.aspx?token=de6453e6-8aa2-4e28-b56c-5e30699d7b3c&ChunkIID=21351

Neuromuscular complications of statins.

Phys Med Rehabil Clin N Am. 2008 Feb;19(1):47-59, vi. Review.

PMID: 18194749 [PubMed - indexed for MEDLINE]

Peripheral neuropathy and statins.

Prescrire Int. 2007 Dec;16(92):247-8.

PMID: 18092417 [PubMed - indexed for MEDLINE]

http://www.pfizer.com/files/products/uspi_lipitor.pdf

A row of bottles on my shelf

Caused me to analyze myself.

One yellow pill I have to pop

Goes to my heart so it won't stop.

A little white one that I take

Goes to my hands so they won't shake.

The blue ones that I use a lot

Tell me I'm happy when I'm not.

The purple pill goes to my brain

And tells me that I have no pain.

The capsules tell me not to wheeze

Or cough or choke or even sneeze...

The red ones, smallest of them all

Go to my blood so I won't fall.

The orange ones, very big and bright

Prevent my leg cramps in the night.

Such an array of brilliant pills

Helping to manage all kinds of ills.

But what I'd really like to know...........

Is what tells each one where to go!

There's always a lot to be thankful for if

You take time to look for it. For example

I am sitting here thinking how nice it is

That wrinkles don't hurt.